Institute Research Scientist Cell Biology

EDUCATION:
Required: Master's degree in biology, biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field.

Preferred: PhD, MD or equivalent degree in Biology, Cell Biology, Pharmacology or related field.

EXPERIENCE: 
Required: Six years' experience of relevant research experience in laboratory. With a PhD in a natural science or Medical degree, two years of required experience. With a Bachelor's, ten years of relevant research experience in laboratory.

Preferred: Relevant research and management experience beyond post-doctoral research maintaining hands-on experience. Industry R&D experience is preferred. 

1.Demonstrated ability to lead independently research activities. Experience advancing novel program from discovery into clinical development is preferred.
2.Extensive knowledge in cancer biology including cell signaling, metabolism, epigenetics, and immune-oncology.
3.Experience using genetic (e.g. RNAi, CRISPR-Cas9, cDNAs) and pharmacological (e.g. small molecule inhibitors or antibodies) approaches to study target biology and biomarker validation is essential.
4.Experience with characterization of tumor biology of in vivo models including subcutaneous and orthotopic xenografts or genetically engineered models of cancer.
4.Deep understanding of preclinical PK/PD/efficacy relationships as they relate to small molecule drug discovery in oncology; translation of findings to the clinic. 
5.Knowledge of preclinical and clinical biomarker discovery and development.
6.Demonstrated ability to plan research activities and timelines.
7.Experience working in highly matrixed organization.
8.Ability to work well under pressure and drive projects that impact critical timelines is essential.
9.Outstanding written and oral communication skills are essential.
10. A collaborative attitude is essential for this position.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html