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Principal Institute Research Scientist - Drug Discovery, Biology & Translation
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Education
Required: PhD in one of the natural sciences or related field or Medical degree.
Experience
Required: Seven years experience of relevant research experience in lab.
Ideal Candidate will possess the following:
1. MD or PhD with over 7 years of relevant post-degree experience in a pharmaceutical/biotech environment.
2. Evidence of utilization of cancer genomics to inform on target discovery, validation and/or clinical positioning of development drug candidates.
3. Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing biochemistry, cellular and molecular biology methods and assays to drive program biology.
4. Experience utilizing mouse models of cancer to enable target discovery, validation, drug development and/or translational biology.
5. Experience working with chemists, in vitro and in vivo pharmacologists to develop and utilize assays in support of the development of small molecules for target validation and as part of lead optimization.
6. Extensive knowledge and experience in areas of tumor biology including, but not limited to immune oncology, oncogenic signaling, cancer metabolism, epigenetic deregulation, apoptosis and/or DNA damage and repair as evidenced by publication in peer-reviewed journals.
7. Strong data analysis skills, ability to interpret results, design of follow-up experiments, troubleshoot issues with assay performance, and effectively present results and conclusions to co-workers, collaborators and senior leadership.
8. Evidence of leading multi-functional teams of scientists to deliver on program objectives.
9. Evidence of independent thinking and leadership skills.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
