Principal Institute Research Scientist Medicinal Chemistry

EDUCATION:

Required: PhD in one of the natural sciences or related field or Medical degree. 

EXPERIENCE:
Required: Five years experience of relevant research experience in lab.

Preferred: The ideal candidate will have a PhD in Organic Chemistry, postdoctoral experience in organic synthesis and 10-15 years of experience working in biopharma company medicinal chemistry labs. Strong knowledge of contemporary synthetic organic chemistry, with a demonstrated track record of creative independent problem-solving. Strong familiarity with the latest hit-finding techniques, included DNA-encoded libraries, fragment screening and affinity-selection mass spectrometry methods, with demonstrated success moving hits into lead optimization. Skilled experimentalist with demonstrated ability to conduct challenging multi-step organic chemistry synthesis and overcome synthetic hurdles, trained in various purification and analytical techniques. Strong publication record in peer reviewed journals. Familiarity with automated and computational chemistry, including datamining software. Experience mentoring and managing chemists and leading hit-to-lead exercises, as well as knowledge of the drug discovery process, is required. Excellent oral and written communication skills and organizational skills are a must. Familiarity with relevant biological disciplines and ability to integrate knowledge from these areas into the design of new bioactive compounds.

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