Senior Research Scientist – Cancer Biology

Education

Required: Master's degree in Biology, Biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field. Preferred: PhD in one of the natural sciences or related field or Medical degree.

Experience

Required: Eight years experience of relevant research experience in lab. With preferred degree, three years of required experience.

Preferred Candidate will possess the following:

1.    MD or PhD with over 2 years of relevant post-degree experience in a pharmaceutical/biotech environment.
2.    Evidence of successfully leading multiple translational biology for programs that advanced into the clinic, including biomarker discovery and validation to measure target engagement, biology of response and patient selection.
3.    Evidence of utilization of cancer genomics to inform on clinical positioning of development drug candidates.  
4.    Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing biochemistry, cellular and molecular biology methods and assays to drive program biology.
5.    Experience utilizing mouse models of cancer to enable target discovery, validation, drug development and/or translational biology.
6.    Experience working with chemists, in vitro and in vivo pharmacologists to develop and use assays in support of the development of therapeutics.
7.    Extensive knowledge and experience in areas of tumor biology including, but not limited to immune oncology, oncogenic signaling, cancer metabolism, epigenetic deregulation, apoptosis and/or DNA damage and repair as evidenced by publication in peer-reviewed journals.
8.    Strong data analysis skills, ability to interpret results, design of follow-up experiments, troubleshoot issues with assay performance, and effectively present results and conclusions to co-workers, collaborators and senior leadership.
9.    Evidence of leading multi-functional teams of scientists to deliver on program objectives.
10.    Evidence of independent thinking and leadership skills.
11.    Evidence of mentoring and managing PhD scientists is a plus.  

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html