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Institute Associate Scientist III, Translational Biology
UT MD Anderson is home to the Therapeutics Discovery Division, a multidisciplinary engine designed to accelerate the development of innovative therapies. Within this division, the RADIATE platform serves as an industrialized translational research unit focused on advancing radiopharmaceutical drug discovery and development through patient-centered research, cutting-edge science, and strong clinical collaboration.
The Institute Associate Scientist III, Translational Biology – RADIATE plays a key role in this environment, contributing to the advancement of investigational diagnostics and therapies. The Institute Associate Scientist III, Translational Biology – RADIATE works closely with cross-functional teams to execute studies that bridge discovery and clinical application, while the Institute Associate Scientist III, Translational Biology – RADIATE helps drive scientific progress from concept through development.
UT MD Anderson is a leading institution focused on cancer care, research, education, and prevention. With a unique structure that integrates research and clinical expertise, UT MD Anderson enables rapid translation of discoveries into impactful therapies. The Institute Associate Scientist III, Translational Biology – RADIATE operates within a fast-paced, milestone-driven environment that emphasizes collaboration, innovation, and scientific excellence to bring life-saving treatments to patients more efficiently.
The ideal candidate will typically have a strong background in translational biology, preclinical research, or related scientific disciplines, with hands-on experience in in vivo and in vitro models, pharmacological studies, and imaging analysis. Experience in executing studies, interpreting data, and maintaining high laboratory standards is essential. Relevant education, laboratory experience, and familiarity with animal models and imaging technologies are expected.
KEY FUNCTIONS:
* Under minimal supervision, assists with validating and utilizing novel in vivo xenograft and allograft models.
* Doses animals and analyzes the outcome of pharmacokinetic, pharmacodynamic and efficacy studies.
* Performs survival and non-survival animal surgeries for specimen collection and characterization.
Utilizes non-invasive imaging.
* Analyzes PET and SPECT data and help with preparation of written and oral reports to project teams.
* Maintains high laboratory standards regarding quality and safety.
* Maintains research records and laboratory notes.
* Other duties as assigned.
EDUCATION
- Required: Bachelor's Degree Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field.
- Preferred: Master's Degree Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field.
WORK EXPERIENCE
- Required: Three years relevant research experience in a lab. One year experience with preferred degree.
- Preferred: In vivo pharmacology experience including animal handling, dosing, and conducting drug PK/PD and efficacy studies with mice is required; experience with radiation for imaging and/or therapy is preferred.
Experience with in vivo models including subcutaneous and orthotopic xenografts and/or genetically engineered models of cancer.
Experience maintaining cell lines in tissue culture, preparing reagents and dosing solutions.
Hands-on experience administering test agents by gavage or intravenous and intraperitoneal injections.
Ability to perform tumor measurements.
Prior experience with minor animal survival and non-survival surgery for specimen collection and characterization.
Experience with in vivo imaging modalities and the evaluation of tissues and biological fluids for molecular and/or biochemical endpoints are desired.
Experience with PET/CT SPECT/CT animal imaging.
- The position requires a highly self-motivated individual, with outstanding organizational skills, the ability to effectively present results and conclusions to co-workers, collaborators, and manager. Ability to work well under pressure and drive personal and team objectives that impact critical timelines is expected. A collaborative attitude is essential for this position.
The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.
This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
