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Research Laboratory Coordinator - Immunology

129967 Requisition #
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The Immunology department at MD Anderson Cancer Center seeks to determine the fundamental cellular and molecular mechanisms of a wide range of processes by which the body recognizes and eliminates pathogens and use these findings to unleash the patient’s own immune system against previously treatment-resistant cancers. Treating the immune system rather than the cancer itself, the therapeutics developed are applicable to many cancers.

Key Functions

Tissue Culture

  1. Processing of human tissues (blood, bone marrow and/or tumors) by ficoll gradient (blood, bone marrow) or enzymatic digestion (tumors).
  2. Preparation of cells for immediate analysis or cryogenic storage for later analysis.
  3. Maintenance of cell cultures of tumor cell lines for assays. Must have the ability to observe and identify cell changes under the microscope, determine cell counts and cell viability.
  4. Knowledge of regular assays for the immune monitoring of clinical samples (RNA and DNA purification, Nanostring, 10x Genomics, Flowcytometry, Mass Cytometry, Luminex/MSD multiplex cytokine/chemokine assays, ELISPOT). 

Laboratory Functions

  1. Coordinates and provides bench level supervision of projects.
  2. Maintains good working relationship with other laboratory membersand is available to answer questions/troubleshoot problems as issues arise. Provides technical guidance and assistance concerning work methods, the use of equipment and techniques, and the analysis of results.
  3. Explains to staff members the scientific protocols currently being employed in the laboratory. 
  4. Trains new staff. 
  5. Plans and reviews laboratory results and operations on an ongoing basis to determine areas for improvement.
  6. Actively supports and complies with laboratory policies and procedures.
  7. Creates, revises and implements laboratory SOPs and data/inventory management systems.
  8. Coordinates sample accrual and immunomonitoring needs with PIs across MDACC and outside collaborative institutions. Attends meetings as necessary to carry out these needs and informs internal personnel ofpertinent information.
  9. Provides technical expertise, consultation, and leadership to scientific professionals and collaborators within area of specialty.
  10. Sets scope of assays, deadlines and FTE and supply needs for major projects.
  11. Analyzes, packages, and reports data to manager and clients.
  12. Designs and implements new research concepts, protocols, and procedures.
  13. Maintains current knowledge of technological developments and trends in area of specialty; identifies current and future technology needs, and introduces and establishes innovative technology to directly support ongoing research activities.
  14. Knowledge of safety concerns when working with human samples.
  15. Exercises alertness and careful attention to avoid injury to self and others from chemicals and hazardous materials and disposable glassware used in the laboratory.
  16. Reads literature and confers with supervisor regarding new procedures and modifies them according to the needs of the project.
  17. Participates in and helps organize meetings and presents data where necessary.
  18. Works late hours and weekends as needed.

Laboratory Maintenance
  1. Knowledge of the utilization and maintenance of the majority of laboratory equipment.
  2. Maintains computerized information systems and participates in their development.
  3. Monitors and anticipates laboratory needs, oversees inventory maintenance, orders supplies, reagents & equipment for the lab.
  4. Maintains an up-to-date, organized, and legible laboratory journal that records all experiments in detail.
  5. Works with Environmental Health & Safety to comply with all institutional requirements for the lab.

Required: Bachelor's degree in one of the natural sciences or related field.

Preferred: Master's degree in one of the natural sciences or related field.


Required: Five years of experience in scientific, research or clinical laboratory to include three years in a lead/supervisory capacity. With preferred degree, three years of required experience in a lead/supervisory capacity.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

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